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The following academic papers on Ewing sarcoma have been published in peer-reviewed journals. Click on the links to read a summary of each paper.

2021

Jing Li, Shunya Ohmura, Aruna Marchetto, Martin F. Orth, Roland Imle, Marlene Dallmayer, Julian Musa, Maximilian M. L. Knott, Tilman L. B. H枚lting, Stefanie Stein, Cornelius M. Funk, Ana Sastre, Javier Alonso, Felix Bestvater, Merve Kasan, Laura Romero-P茅rez, Wolfgang Hartmann, Andreas Ranft, Ana Banito, Uta Dirksen, Thomas Kirchner, Florencia Cidre-Aranaz & Thomas G. P. Gr眉newald

Lisa Bierbaumer, Anna M. Katschnig, Branka Radic-Sarikas, Maximilian O. Kauer, Jeffrey A. Petro, Sandra H枚gler, Elisabeth Gurnhofer, Gloria Pedot, Beat W. Sch盲fer, Raphaela Schwentner, Karin M眉hlbacher, Florian Kromp, Dave N. T. Aryee, Lukas Kenner, Aykut Uren, and Heinrich Kovar

Stefan K. Z枚llner, James F. Amatruda, Sebastian Bauer, St茅phane Collaud, Enrique de 脕lava, Steven G. DuBois, Jendrik Hardes, Wolfgang Hartmann, Heinrich Kovar, Markus Metzler, David S. Shulman, Arne Streitb眉rger, Beate Timmermann, Jeffrey A. Toretsky, Yasmin Uhlenbruch, Volker Vieth, Thomas G. P. Gr眉newald, and Uta Dirksen

Peter Peneder, Adrian M. St眉tz, Didier Surdez, Manuela Krumbholz, Sabine Semper, Mathieu Chicard, Nathan C. Sheffield, Gaelle Pierron, Eve Lapouble, Marcus T枚tzl, Bekir Erg眉ner, Daniele Barreca, Andr茅 F. Rendeiro, Abbas Agaimy, Heidrun Boztug, Gernot Engstler, Michael Dworzak, Marie Bernkopf, Sabine Taschner-Mandl, Inge M. Ambros, Ola Myklebost, Perrine Marec-B茅rard, Susan Ann Burchill, Bernadette Brennan, Sandra J. Strauss, Jeremy Whelan, Gudrun Schleiermacher, Christiane Schaefer, Uta Dirksen, Caroline Hutter, Kjetil Boye, Peter F. Ambros, Olivier Delattre, Markus Metzler, Christoph Bock & Eleni M. Tomazou

"Sequencing of cell-free DNA in the blood of cancer patients (liquid biopsy) provides attractive opportunities for early diagnosis, assessment of treatment response, and minimally invasive disease monitoring." This study included 200 plasma samples from 95 patients with ES, most of whom took part in the EWING2008 trial.听

They showed that "whole-genome sequencing of cfDNA (when combined with suitable computational methods, some of which we developed here) provides a one-size-fits-all assay for liquid biopsy analysis, allowing us to: (i) detect tumor-derived DNA with high sensitivity and without requiring any somatic mutations or CNAs; (ii) distinguish between different cancer types based on their characteristic epigenetic signatures; (iii) monitor CNAs and disease progression over time; (iv) assess treatment-induced toxicity and organ damage based on cfDNA released from dying cells; and (v) estimate survival and relapse probabilities at diagnosis. Importantly, our approach is practically feasible in a clinical setting, requires less than 10鈥塶g of cfDNA, profits from falling sequencing costs, does not require access of primary tumor tissue, and is informative even in the absence of any genetic alterations".

2018

Ornella Gonzato & Alessandro Gronchi

2015

Selvanathan SP, Graham GT, Erkizan HV, Dirksen U, Natarajan TG, Dakic A, Yu S, Liu X, Paulsen MT, Ljungman ME, Wu CH, Lawlor ER, 脺ren A, Toretsky JA

2014

Kovar H

Marie-C茅cile Le Deley鈬�, Michael Paulussen, Ian Lewis, Bernadette Brennan, Andreas Ranft, Jeremy Whelan, Gw茅na毛l Le Teuff, Jean Michon, Ruth Ladenstein, Perrine Marec-B茅rard, Henk van den Berg, Lars Hjorth, Keith Wheatley, Ian Judson, Heribert Juergens, Alan Craft, Odile Oberlin and Uta Dirksen

2012

Jeremy Whelan, Atia Khan, Anand Sharma, Christian Rothermundt, Palma Dileo, Maria Michelagnoli, Beatrice Seddon, and Sandra Strauss

Womer RB, West DC, Krailo MD, Dickman PS, Pawel BR, Grier HE, Marcus K, Sailer S, Healey JH, Dormans JP, Weiss AR.

2010

Ladenstein R, P枚tschger U, Le Deley MC, Whelan J, Paulussen M, Oberlin O, van den Berg H, Dirksen U, Hjorth L, Michon J, Lewis I, Craft A, J眉rgens H

2006

Juergens C, Weston C, Lewis I, Whelan J, Paulussen M, Oberlin O, Michon J, Zoubek A, Juergens H, Craft A

2003

S.J. Strauss, A. McTiernan, D. Driver, M. Hall-Craggs, A. Sandison, A.M. Cassoni, A. Kilby, M. Michelagnoli, J. Pringle, J. Cobb, T. Briggs, S. Cannon, J. Witt and J.S. Whelan

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