Our group is focused on establishing assays capable of predicting patients at risk of fibrinolytic-induced bleeding, thus allowing for better management of their condition.
In arterial injury causing thrombosis, complement C3a and C5a are strongly correlated whereas they are not correlated in venous thrombosis.
Explaining the discordance of these data is a major focus of our research. Our group aims to characterise the mechanisms of complement activation in thrombosis and devise methods to control inflammation in thrombotic disease.Â